@inbook { WOS:000402908700007,
	title = {Integration of Bacterial Small RNAs in Regulatory Networks},
	booktitle = {ANNUAL REVIEW OF BIOPHYSICS, VOL 46},
	series = {Annual Review of Biophysics},
	volume = {46},
	year = {2017},
	pages = {131-148},
	publisher = {ANNUAL REVIEWS},
	organization = {ANNUAL REVIEWS},
	type = {Review; Book Chapter},
	address = {4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0897 USA},
	abstract = {Small RNAs (sRNAs) are central regulators of gene expression in bacteria, controlling target genes posttranscriptionally by base pairing with their mRNAs. sRNAs are involved in many cellular processes and have unique regulatory characteristics. In this review, we discuss the properties of regulation by sRNAs and how it differs from and combines with transcriptional regulation. We describe the global characteristics of the sRNA-target networks in bacteria using graph-theoretic approaches and review the local integration of sRNAs in mixed regulatory circuits, including feed-forward loops and their combinations, feedback loops, and circuits made of an sRNA and another regulator, both derived from the same transcript. Finally, we discuss the competition effects in posttranscriptional regulatory networks that may arise over shared targets, shared regulators, and shared resources and how they may lead to signal propagation across the network.},
	keywords = {competing RNAs, feed-forward loop, regulatory network, small RNA},
	isbn = {978-0-8243-1846-8},
	issn = {1936-122X},
	doi = {10.1146/annurev-biophys-070816-034058},
	url = {https://doi.org/10.1146/annurev-biophys-070816-034058},
	author = {Nitzan, Mor and Rehani, Rotem and Margalit, Hanah},
	editor = {Dill, KA}
}
